LGD-4 (Ligand): All You Need to Know About the Most Popular SARM

LGD-4 (Ligand) is a selective androgen receptor modulator (SARM) that has been generating a lot of buzz lately among bodybuilders and fitness enthusiasts. Some people are calling it the ultimate muscle-builder, and many claim that it can help you achieve the top of physique transformation. LGD-4 is a powerful new class of androgen receptor modulator, meaning it has the ability to stimulate muscle growth. It’s perfect for bodybuilders who want an edge in their training regiment or competitive athletes looking to get more power on the field. If you’re curious about LGD-4 and whether or not it can help you achieve your fitness goals, then read on to learn more about it.

What is LGD-4 (Ligand)?

LGD-4 is a SARM from the LGD group of SARMs which have a high affinity for androgen receptors. In addition to stimulating muscle growth, LGD-4 also increases the users strength. LGD also helps to improve bone health and can even prevent bone loss caused by some diseases.

LGD-4 causes a positive nitrogen balance. In professional sports, where the difference between winning and losing can sometimes be measured by hundredths of seconds or fractions of inches, athletes are willing to do almost anything to gain an edge. As a result, supplements that improve performance without any side effects are in high demand. LGD-4 is one such supplement, and it’s quickly gaining a reputation for being one of the most powerful and effective SARMs on the market.


How does LGD-4 (Ligand) work?

LGD-4 attaches to the androgen receptor (AR) and causes anabolic activity. It stimulates muscle growth by increasing protein synthesis as well as inhibiting degradation, which leads to increased muscle mass. In addition, LGD-4 also decreases body fat by stimulating lipolysis (the breakdown of fats) and preventing their accumulation. It also has positive effects on overall energy levels and cardio endurance.

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LGD-4 Benefits

Difference Between Ligand and Steroids

SARMs are not hormones, but they function in a similar way, by binding to the androgen receptor. This makes them ideal for muscle growth because clinical studies have shown that LGD-4 can stimulate muscle growth while reducing body fat levels.

LGD-4 stimulates protein synthesis by promoting nitrogen retention in muscles. Increased nitrogen content is often called ‘the building block of protein’ because it plays a critical role in forming new proteins necessary for cell growth, allowing users to enjoy leaner, stronger muscles without experiencing any unwanted side effects such as increased estrogen production seen with testosterone supplementation. Furthermore, SARMs provide endurance benefits, which could be the result of an increase in mitochondria, and organelles within cells that play a vital role in producing energy.

Benefits of LGD-4 (Ligand)

Increase Lean Muscle Mass 

Although compared to testosterone, the effects of this SARM on muscle growth will not be nearly as pronounced. In studies, LGD-4 has been shown to encourage nitrogen retention in muscles, making it easier for users to gain leaner muscles. In particular, one study showed it doubled nitrogen retention, which is crucial for increasing protein synthesis and building lean muscle mass. Users who supplement with this SARM can expect their overall strength levels and muscular endurance to improve as well as their physical appearance.

Reduction of Body Fat Levels 

LGD-4 also has an effect on body fat levels by stimulating lipolysis (the breakdown of fats) and preventing its accumulation. This means that users can enjoy a decrease in body fat percentage while gaining muscle mass. In addition, LGD-4 also has a positive effect on overall energy levels and cardio endurance, making it easier to participate in physical activities for an extended period of time without experiencing fatigue.

Increased Endurance 

LGD-4 also seems to have a positive effect on overall energy levels and cardio endurance. One study showed that it increased running time by 50% in mice when compared to those who did not take the SARM. This could be due to an increase in mitochondria, and organelles within cells that play a vital role in producing energy. With more energy, users can participate in physical activities for an extended period of time without experiencing fatigue.

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How does Ligand compare to other SARM’s?

SARMs are designed to mimic the benefits of testosterone, although their effects are not as great. On paper, LGD-4 is a promising SARM supplement with the ability to promote lean muscle growth. It also has a lower risk of side effects than testosterone replacement therapy. In addition, it does not cause liver damage as was reported by one study involving orally administered RAD140.

Comparatively speaking, Ostarine (MK-2866) seems to have the edge over LGD-4 though since it can be used at therapeutic doses without causing negative consequences such as virilization in women or suppression of natural testosterone production. However, both SARMs show promising results in studies thus far and they’re considered effective supplements for achieving your fitness goals.

LGD-4 stacks well with other supplements. It should be noted that LGD-4 does not require any other supplement to work effectively. However, it stacks well with other supplements for synergistic effects. Some studies suggest that LGD-4 works best in conjunction with MK677. This is because LGD-4 increases growth hormone levels while MK677 stimulates IGF-1, another anabolic hormone. Furthermore, the two compounds have different mechanisms of action which can produce greater effects when used together.

How to take LGD-4?

LGD-4 is typically taken orally, and the dosage will vary depending on your needs and goals. As with any new supplement, it’s always best to start out with a lower dose and increase gradually as needed. Most users find that a dose of 5mg to 10mg per day is sufficient for achieving their desired results. LGD-4 should be taken on an empty stomach, either first thing in the morning or 2 hours before working out. It can be cycled for 8 weeks on and then 4 weeks off.


Stacking options for Ligand

SARMs like LGD-4 can be stacked with other supplements for synergistic effects. Some users stack it with MK677 and S4 (Andarine) as mentioned above. In addition, it stacks well with Ostarine, Cardarine (GW501516), YK11, AICAR, and SR9009 for extra benefits.

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For a bulking cycle, consider stacking either Ostarine MK-2866 or Testolone (RAD140) together with LGD-4. This will help you achieve your fitness goals faster by boosting your protein synthesis. You’ll gain lean muscle mass which you can maintain after discontinuing the use of SARMs.

For a cutting cycle, consider stacking S-4 (Andarine) with LGD-4. Both supplements are non-methylated which means they don’t have harsh effects on your liver. They are also both supposed to increase dopamine levels which will encourage an increased sense of alertness and energy for working out. You’ll be able to maintain your lean muscle mass while burning away unwanted body fat.

Alternatives to LGD-4

If you’re not interested in taking LGD-4033, there are other SARMs that you can try. Ostarine (MK-2866) is a popular SARM that has been shown to be effective in increasing muscle mass and strength. It’s well tolerated by both men and women and doesn’t require any PCT (post-cycle therapy) when discontinued.

Alternatively, you could try Anavar, an anabolic steroid that has been shown to build higher amounts of lean muscle tissue whilst also having minimal risk of side effects due to its mild nature. Anavar is one of the most popular oral anabolic steroids around and has been used for decades by both male and female users due to its proven track record of results.


Cycle and PCT for Ligand

As with all SARMs, it’s recommended to do a PCT if you choose to take LGD-4 for more than 8 weeks. A standard PCT is usually 4-6 weeks and involves taking an AI (aromatase inhibitor) such as Anastrozole or Letrozole. This will lower the amount of estrogen in your blood which ensures that your gains stay after you discontinue taking SARMs like LGD-4. It also helps prevent any potential side effects such as gyno.